منابع مشابه
Effect of maternal fluoxetine exposure on lung, heart and kidney development in rat neonates
Objective(s): Depression during pregnancy negatively affects fetal development. Fluoxetine as a selective serotonin reuptake inhibitor (SSRIs) is used for treatment of gestational depression. This study is trying to determine the effects of fluoxetine on the renal, heart and lung development.Materials and Methods: Fifteen pregnant rats were treated with fluoxetine at 7 mg/kg from days 0 to 21 o...
متن کاملP-180: The Fate of Motherhood, Fetuses and Neonates in Drug Addicted Pregnant Women
Background: Pregnancy in opioid-dependent women is a major public health issue. According to a national household survey in 2001, 3.7% of pregnant women in the United States used illicit drugs. In 2009 this number increased to 4.5% . Women who are afflicted by opioid addiction form a highly vulnerable group of patients frequently facing unplanned pregnancy with adverse outcomes including perina...
متن کاملBlack Box Warnings in Prescription Drug Labeling:
Prescription drugs are unavoidably associated with adverse effects, but the benefits of using such drugs outweigh the accompanying risks so long as the expert judgment of a licensed practitioner is first applied in the decision to use a drug for a particular patient. Most risks for prescription drugs appear in descending order of importance in the drug’s labeling, i.e., the package insert. The ...
متن کاملPediatric information in drug product labeling.
To the Editor: The dearth of information on drugs for children led to children being called “therapeutic orphans.” In 1975, Wilson determined that 78% of drug labeling had inadequate pediatric information. In 1999, Wilson summarized 25 years of efforts to get pediatric information into labeling and extended his analysis. In the decade after Wilson’s review, regulations and legislation have led ...
متن کاملUnlicensed and off label drug use in neonates.
AIM To determine the extent of use of drugs that are either not licensed (unlicensed), or are outside the terms of their product licence (off label) in a neonatal intensive care unit. METHODS A prospective study was conducted over 13 weeks. RESULTS 455 prescription episodes were administered to 70 babies. 63 (90%) patients were given a drug that was either unlicensed or used in an off label...
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ژورنال
عنوان ژورنال: JAMA Pediatrics
سال: 2014
ISSN: 2168-6203
DOI: 10.1001/jamapediatrics.2013.4208